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Chemical structure of LNT 1

GC50481

LNT 1

Also known as 1-(2,3-dihydro-1,4-benzodioxin-3-ylmethyl)-3-hydroxythieno[3,2-d]pyrimidine-2,4-dione

LNT 1 (compound 1) is a flap endonuclease 1 (FEN1) inhibitor· LNT 1 binds to the active site of FEN1 and partly achieves inhibition by the co-ordination of Mg2+ ions

ChemicalCAS824983-91-7MW332.33FormulaC15H12N2O5S
CAS number
824983-91-7
Molecular weight
332.33
Formula
C15H12N2O5S
Solubility
Soluble in DMSO
InChIKey
MXQGCMQXTPTJJT-UHFFFAOYSA-N
Catalogue number
GC50481
Brand
GLPBIO
Computed properties PubChem CID 11652865 · XLogP 1.8 · TPSA 108 Ų · H-bond donors 1
XLogP
1.8
TPSA
108 Ų
H-bond donors
1
H-bond acceptors
6
Rotatable bonds
2
Heavy atoms
23

SMILES C1C(OC2=CC=CC=C2O1)CN3C4=C(C(=O)N(C3=O)O)SC=C4

Computed descriptors from PubChem (CID 11652865), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

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