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Chemical structure of UNC 2399

GC50082

UNC 2399

Also known as 6-[6-[4-[3-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-[5-[(3aS,4S,6aR)-2-oxo-1,3,3a,4,6,6a-hexahydrothieno[3,4-d]imidazol-4-yl]pentanoylamino]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]propanoyl]piperazin-1-yl]-3-pyridinyl]-N-[(6-methyl-2-oxo-4-propyl-1H-pyridin-3-yl)methyl]-1-propan-2-ylindazole-4-carboxamide

UNC 2399, a biotinylated UNC1999, is a selective EZH2 degrader, maintaining high in vitro potency for EZH2, with an IC50 of 17 nM

ChemicalCAS2412791-72-9MW1353.66FormulaC67H104N10O17S
CAS number
2412791-72-9
Molecular weight
1353.66
Formula
C67H104N10O17S
Solubility
Soluble in DMSO
InChIKey
PSDIDGKZEPMSHC-FRQYIUQJSA-N
Catalogue number
GC50082
Brand
GLPBIO
Computed properties PubChem CID 118732748 · XLogP 1.5 · TPSA 319 Ų · H-bond donors 5
XLogP
1.5
TPSA
319 Ų
H-bond donors
5
H-bond acceptors
21
Rotatable bonds
52
Heavy atoms
95

SMILES CCCC1=C(C(=O)NC(=C1)C)CNC(=O)C2=C3C=NN(C3=CC(=C2)C4=CN=C(C=C4)N5CCN(CC5)C(=O)CCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCNC(=O)CCCC[C@H]6[C@@H]7[C@H](CS6)NC(=O)N7)C(C)C

Computed descriptors from PubChem (CID 118732748), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.