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Chemical structure of S6K-18

GC49763

S6K-18

Also known as 5-tert-butyl-2-(1H-indazol-5-ylcarbamoylamino)thiophene-3-carboxylic acid

S6K-18 is a potent and selective p70S6K1 inhibitor with an IC50 of 52 nM

ChemicalCAS1265789-88-5MW358.4FormulaC17H18N4O3S
CAS number
1265789-88-5
Molecular weight
358.4
Formula
C17H18N4O3S
Solubility
DMF: 1 mg/ml,DMSO: 2 mg/ml,Ethanol: 1 mg/ml,PBS (pH 7·2): insol
InChIKey
BSRFCMMJUFQEOX-UHFFFAOYSA-N
Catalogue number
GC49763
Brand
GLPBIO
Computed properties PubChem CID 53317853 · XLogP 3.9 · TPSA 135 Ų · H-bond donors 4
XLogP
3.9
TPSA
135 Ų
H-bond donors
4
H-bond acceptors
5
Rotatable bonds
4
Heavy atoms
25

SMILES CC(C)(C)C1=CC(=C(S1)NC(=O)NC2=CC3=C(C=C2)NN=C3)C(=O)O

Computed descriptors from PubChem (CID 53317853), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
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Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.