GC48493
PCI 45227
Also known as 1-[(3R)-3-[4-amino-3-(4-phenoxyphenyl)pyrazolo[3,4-d]pyrimidin-1-yl]piperidin-1-yl]-2,3-dihydroxypropan-1-one
PCI 45227 (PCI-45227) is a dihydrodiolactive metabolite of Ibrutinib, has inhibitory activity towards BTK approximately 15 times lower than that of ibrutinib
ChemicalCAS1654820-87-7MW474.5FormulaC25H26N6O4
- CAS number
- 1654820-87-7
- Molecular weight
- 474.5
- Formula
- C25H26N6O4
- Solubility
- Methanol： soluble
- InChIKey
- NWKPMPRXJGMTKQ-DIAVIDTQSA-N
- Catalogue number
- GC48493
- Brand
- GLPBIO
Computed properties PubChem CID 91971609 · XLogP 1.7 · TPSA 140 Ų · H-bond donors 3
- XLogP
- 1.7
- TPSA
- 140 Ų
- H-bond donors
- 3
- H-bond acceptors
- 8
- Rotatable bonds
- 6
- Heavy atoms
- 35
SMILES C1C[C@H](CN(C1)C(=O)C(CO)O)N2C3=NC=NC(=C3C(=N2)C4=CC=C(C=C4)OC5=CC=CC=C5)N
Computed descriptors from PubChem (CID 91971609), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.
Ordering in Israel
- Lead time
- Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
- Pricing
- Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
- Documents
- Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
- Who we serve
- Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.
- Questions
- WhatsApp · +972-55-990-7576 · orders@labo.co.il