GC47055
CAY10749
Also known as 4-[[3-[2-[6-amino-4-(trifluoromethyl)-3-pyridinyl]-4-morpholin-4-yl-6,8-dihydro-5H-pyrido[3,4-d]pyrimidine-7-carbonyl]-4-fluorophenyl]methyl]-2H-phthalazin-1-one
CAY10749 (compound 15) is a potent PARP/PI3K inhibitor with pIC50 values of 8·22, 8·44, 8·25, 6·54, 8·13, 6·08 for PARP-1, PARP-2, PI3Kα, PI3Kβ, PI3Kδ, and PI3Kγ, respectively· CAY10749 is a highly effective anticancer compound targeted against a wide range of oncologic diseases
ChemicalCAS2337386-47-5MW660.6FormulaC33H28F4N8O3
- CAS number
- 2337386-47-5
- Molecular weight
- 660.6
- Formula
- C33H28F4N8O3
- Solubility
- DMF： 11mg/mL,DMF：PBS (pH 7·2) (1：2)： 0·3mg/mL,DMSO： 10mg/mL
- InChIKey
- LIQDGVXNWJAUNO-UHFFFAOYSA-N
- Catalogue number
- GC47055
- Brand
- GLPBIO
Computed properties PubChem CID 146014481 · XLogP 3.2 · TPSA 139 Ų · H-bond donors 2
- XLogP
- 3.2
- TPSA
- 139 Ų
- H-bond donors
- 2
- H-bond acceptors
- 13
- Rotatable bonds
- 5
- Heavy atoms
- 48
SMILES C1CN(CC2=C1C(=NC(=N2)C3=CN=C(C=C3C(F)(F)F)N)N4CCOCC4)C(=O)C5=C(C=CC(=C5)CC6=NNC(=O)C7=CC=CC=C76)F
Computed descriptors from PubChem (CID 146014481), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.
Ordering in Israel
- Lead time
- Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
- Pricing
- Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
- Documents
- Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
- Who we serve
- Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.
- Questions
- WhatsApp · +972-55-990-7576 · orders@labo.co.il