GC46171
ML-396
Also known as N-[3-chloro-4-[(5-chloro-2-pyridinyl)oxy]phenyl]pyridine-2-carboxamide
ML-396 is a positive allosteric modulator of group III mGluRs with EC50 values of 108, 146, and 128 nM for mGluR4, mGluR7, and mGluR8, respectively in calcium mobilization assays
ChemicalCAS1630936-95-6MW360.2FormulaC17H11Cl2N3O2
- CAS number
- 1630936-95-6
- Molecular weight
- 360.2
- Formula
- C17H11Cl2N3O2
- Solubility
- DMSO ： 25 mg/mL (69·41 mM; Need ultrasonic)
- InChIKey
- MZRLPXFGQKQHST-UHFFFAOYSA-N
- Catalogue number
- GC46171
- Brand
- GLPBIO
Computed properties PubChem CID 73058507 · XLogP 4.1 · TPSA 64.1 Ų · H-bond donors 1
- XLogP
- 4.1
- TPSA
- 64.1 Ų
- H-bond donors
- 1
- H-bond acceptors
- 4
- Rotatable bonds
- 4
- Heavy atoms
- 24
SMILES C1=CC=NC(=C1)C(=O)NC2=CC(=C(C=C2)OC3=NC=C(C=C3)Cl)Cl
Computed descriptors from PubChem (CID 73058507), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.
Ordering in Israel
- Lead time
- Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
- Pricing
- Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
- Documents
- Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
- Who we serve
- Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.
- Questions
- WhatsApp · +972-55-990-7576 · orders@labo.co.il