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Chemical structure of DS-437

GC45927

DS-437

Also known as 1-[2-[[(2S,3S,4R,5R)-5-(6-aminopurin-9-yl)-3,4-dihydroxyoxolan-2-yl]methylsulfanyl]ethyl]-3-ethylurea

A dual inhibitor of PRMT5 and PRMT7

ChemicalCAS1674364-87-4MW397.45FormulaC15H23N7O4S
CAS number
1674364-87-4
Molecular weight
397.45
Formula
C15H23N7O4S
Solubility
DMSO : 125 mg/mL (314·50 mM; Need ultrasonic)
InChIKey
CACMCLIHCDTJHL-IDTAVKCVSA-N
Catalogue number
GC45927
Brand
GLPBIO
Computed properties PubChem CID 122178085 · XLogP -0.8 · TPSA 186 Ų · H-bond donors 5
XLogP
-0.8
TPSA
186 Ų
H-bond donors
5
H-bond acceptors
9
Rotatable bonds
7
Heavy atoms
27

SMILES CCNC(=O)NCCSC[C@@H]1[C@H]([C@H]([C@@H](O1)N2C=NC3=C(N=CN=C32)N)O)O

Computed descriptors from PubChem (CID 122178085), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.