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Chemical structure of α-hydroxy Farnesyl Phosphonic Acid

GC45207

α-hydroxy Farnesyl Phosphonic Acid

Also known as (1-hydroxy-3,7,11-trimethyldodeca-2,6,10-trienyl)phosphonic acid

α-hydroxy Farnesyl phosphonic acid is a nonhydrolyzable analog of farnesyl pyrophosphate which acts as a competitive inhibitor of farnesyl transferase (FTase)

ChemicalCAS148796-53-6MW302.4FormulaC15H27O4P
CAS number
148796-53-6
Molecular weight
302.4
Formula
C15H27O4P
Solubility
10 mM Na2CO3: freely soluble,ETOH: >25 mg/ml,PBS pH 7·2: <25 μ g/ml
InChIKey
MONZTFSZTWQCKH-UHFFFAOYSA-N
Catalogue number
GC45207
Brand
GLPBIO
Computed properties PubChem CID 2106 · XLogP 3.1 · TPSA 77.8 Ų · H-bond donors 3
XLogP
3.1
TPSA
77.8 Ų
H-bond donors
3
H-bond acceptors
4
Rotatable bonds
8
Heavy atoms
20

SMILES CC(=CCCC(=CCCC(=CC(O)P(=O)(O)O)C)C)C

Computed descriptors from PubChem (CID 2106), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

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