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Chemical structure of Z-IETD-AFC

GC45181

Z-IETD-AFC

Also known as (4S)-5-[[(2S,3R)-1-[[(2S)-3-carboxy-1-oxo-1-[[2-oxo-4-(trifluoromethyl)chromen-7-yl]amino]propan-2-yl]amino]-3-hydroxy-1-oxobutan-2-yl]amino]-4-[[(2S,3S)-3-methyl-2-(phenylmethoxycarbonylamino)pentanoyl]amino]-5-oxopentanoic acid

Z-IETD-AFC is a fluorogenic substrate for caspase-8 and granzyme B

ChemicalCAS219138-02-0MW821.8FormulaC37H42F3N5O13
CAS number
219138-02-0
Molecular weight
821.8
Formula
C37H42F3N5O13
Solubility
Soluble in DMSO
InChIKey
RCIFCAJYIPUCJW-QXPVPWKFSA-N
Catalogue number
GC45181
Brand
GLPBIO
Computed properties PubChem CID 71312079 · XLogP 1.7 · TPSA 276 Ų · H-bond donors 8
XLogP
1.7
TPSA
276 Ų
H-bond donors
8
H-bond acceptors
16
Rotatable bonds
20
Heavy atoms
58

SMILES CC[C@H](C)[C@@H](C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CC(=O)O)C(=O)NC1=CC2=C(C=C1)C(=CC(=O)O2)C(F)(F)F)NC(=O)OCC3=CC=CC=C3

Computed descriptors from PubChem (CID 71312079), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
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Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
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Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.