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Chemical structure of VEGFR2 Kinase Inhibitor II

GC45142

VEGFR2 Kinase Inhibitor II

Also known as (3Z)-5-bromo-3-(4,5,6,7-tetrahydro-1H-indol-2-ylmethylidene)-1H-indol-2-one

Vascular endothelial growth factor receptor 2 (VEGFR2, also known as KDR and FLK1) is a receptor tyrosine kinase that regulates angiogenesis, vascular development, and embryonic hematopoiesis in response to VEGF isoforms A, C, and D

ChemicalCAS288144-20-7MW343.2FormulaC17H15BrN2O
CAS number
288144-20-7
Molecular weight
343.2
Formula
C17H15BrN2O
Solubility
DMF： 20 mg/ml,DMSO： 10 mg/ml
InChIKey
RFHPWPWVGFSLOP-ZROIWOOFSA-N
Catalogue number
GC45142
Brand
GLPBIO
Computed properties PubChem CID 5329155 · XLogP 3.6 · TPSA 44.9 Ų · H-bond donors 2
XLogP
3.6
TPSA
44.9 Ų
H-bond donors
2
H-bond acceptors
1
Rotatable bonds
1
Heavy atoms
21

SMILES C1CCC2=C(C1)C=C(N2)/C=C\3/C4=C(C=CC(=C4)Br)NC3=O

Computed descriptors from PubChem (CID 5329155), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.