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Chemical structure of TMP-153

GC45060

TMP-153

Also known as 1-[4-(2-chlorophenyl)-6,7-dimethylquinolin-3-yl]-3-(2,4-difluorophenyl)urea

Acyl-CoA:cholesterol acyltransferase (ACAT) catalyses the esterification of excess cellular cholesterol with fatty acids and is important for intestinal cholesterol absorption, hepatic lipoprotein secretion, and cholesterol accumulation in vascular tissues

ChemicalCAS128831-46-9MW437.9FormulaC24H18ClF2N3O
CAS number
128831-46-9
Molecular weight
437.9
Formula
C24H18ClF2N3O
Solubility
DMF： 10 mg/ml,DMSO： 30 mg/ml
InChIKey
FFKNNBNIAHVVCU-UHFFFAOYSA-N
Catalogue number
GC45060
Brand
GLPBIO
Computed properties PubChem CID 125289 · XLogP 5.9 · TPSA 54 Ų · H-bond donors 2
XLogP
5.9
TPSA
54 Ų
H-bond donors
2
H-bond acceptors
4
Rotatable bonds
3
Heavy atoms
31

SMILES CC1=CC2=C(C(=CN=C2C=C1C)NC(=O)NC3=C(C=C(C=C3)F)F)C4=CC=CC=C4Cl

Computed descriptors from PubChem (CID 125289), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
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Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
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