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Chemical structure of RBI-257 Maleate

GC44807

RBI-257 Maleate

Also listed as RBI 257 (maleate)

RBI 257 is a potent dopamine D4 receptor antagonist (Ki = 0·3 nM) that is selective over D2L, D3, D2-like, and D1 receptors by 1,721-, 439-, 1,336-, and 8,576-fold, respectively

ChemicalCAS911378-38-6MW581.4FormulaC21H28IN3O•C4H4O4
CAS number
911378-38-6
Molecular weight
581.4
Formula
C21H28IN3O•C4H4O4
Solubility
DMF: 30 mg/ml,DMSO: 30 mg/ml,DMSO:PBS (pH 7·2) (1:1): 0·5 mg/ml
InChIKey
NIRRRTUKUHIOTQ-BTJKTKAUSA-N
Catalogue number
GC44807
Brand
GLPBIO
Computed properties PubChem CID 16219927 · TPSA 103 Ų · H-bond donors 2 · H-bond acceptors 8
TPSA
103 Ų
H-bond donors
2
H-bond acceptors
8
Rotatable bonds
8
Heavy atoms
34

SMILES CC(C)OC1=C(N=CC=C1)N(C)C2CCN(CC2)CC3=CC=C(C=C3)I.C(=C\C(=O)O)\C(=O)O

Computed descriptors from PubChem (CID 16219927), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
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Pricing
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Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
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