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Chemical structure of Pioglitazone (potassium salt)

GC44645

Pioglitazone (potassium salt)

Also known as potassium 5-[[4-[2-(5-ethyl-2-pyridinyl)ethoxy]phenyl]methyl]-1,3-thiazolidin-3-ide-2,4-dione

Pioglitazone (U 72107) potassium is an orally active and selective PPARγ (peroxisome proliferator-activated receptor) agonist with high affinity binding to the PPARγ ligand-binding domain with EC50 of 0·93 μM and 0·99 μM for human and mouse PPARγ, respectively

ChemicalCAS1266523-09-4MW394.5FormulaC19H19N2O3S•K
CAS number
1266523-09-4
Molecular weight
394.5
Formula
C19H19N2O3S•K
Solubility
DMF: 30 mg/ml,DMSO: 10 mg/ml,Ethanol: 10 mg/ml
InChIKey
YRUUYXLNBAJFIM-UHFFFAOYSA-M
Catalogue number
GC44645
Brand
GLPBIO
Computed properties PubChem CID 56653040 · TPSA 82.6 Ų · H-bond donors 0 · H-bond acceptors 6
TPSA
82.6 Ų
H-bond donors
0
H-bond acceptors
6
Rotatable bonds
7
Heavy atoms
26

SMILES CCC1=CN=C(C=C1)CCOC2=CC=C(C=C2)CC3C(=O)[N-]C(=O)S3.[K+]

Computed descriptors from PubChem (CID 56653040), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

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