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Chemical structure of p38 MAPK Inhibitor

GC44530

p38 MAPK Inhibitor

Also known as 2-(4-chlorophenyl)-4-(4-fluorophenyl)-5-pyridin-4-yl-1H-pyrazol-3-one

p38 MAPK inhibitor is a potent inhibitor of p38 MAP kinase (IC50 = 35 nM)

ChemicalCAS219138-24-6MW365.8FormulaC20H13ClFN3O
CAS number
219138-24-6
Molecular weight
365.8
Formula
C20H13ClFN3O
Solubility
DMF： 5 mg/ml,DMSO： 5 mg/ml,DMSO：PBS(pH7·2) (1：1)： 0·5 mg/ml,Ethanol： 0·3 mg/ml
InChIKey
DZFBYHUKZSRPHU-UHFFFAOYSA-N
Catalogue number
GC44530
Brand
GLPBIO
Computed properties PubChem CID 4665 · XLogP 4.4 · TPSA 45.2 Ų · H-bond donors 1
XLogP
4.4
TPSA
45.2 Ų
H-bond donors
1
H-bond acceptors
4
Rotatable bonds
3
Heavy atoms
26

SMILES C1=CC(=CC=C1C2=C(NN(C2=O)C3=CC=C(C=C3)Cl)C4=CC=NC=C4)F

Computed descriptors from PubChem (CID 4665), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
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Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.