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Chemical structure of P053

GC44529

P053

Also known as (2S)-2-amino-4-[4-[(3,4-dichlorophenyl)methoxy]phenyl]-2-methylbutan-1-ol

P053 is an inhibitor of ceramide synthase 1 (CerS1; IC50s = 0·54 and 0·46 μM for human and mouse CerS1, respectively)

ChemicalCAS2748196-63-4MW354.3FormulaC18H21Cl2NO2
CAS number
2748196-63-4
Molecular weight
354.3
Formula
C18H21Cl2NO2
Solubility
DMF: 30 mg/mL,DMSO: 30 mg/mL,Ethanol: 30 mg/mL
InChIKey
ZQQHXJCIFGMUPY-SFHVURJKSA-N
Catalogue number
GC44529
Brand
GLPBIO
Computed properties PubChem CID 137700518 · XLogP 3.9 · TPSA 55.5 Ų · H-bond donors 2
XLogP
3.9
TPSA
55.5 Ų
H-bond donors
2
H-bond acceptors
3
Rotatable bonds
7
Heavy atoms
23

SMILES C[C@](CCC1=CC=C(C=C1)OCC2=CC(=C(C=C2)Cl)Cl)(CO)N

Computed descriptors from PubChem (CID 137700518), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
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Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.