Loading...
Chemical structure of ML-345

GC44225

ML-345

Also known as 5-fluoro-2-(2-morpholin-4-yl-5-morpholin-4-ylsulfonylphenyl)-1,2-benzothiazol-3-one

Insulin-degrading enzyme (IDE) is a thiol-sensitive zinc-metallopeptidase that acts as the major insulin-degrading protease in vivo, mediating the termination of insulin signaling

ChemicalCAS1632125-79-1MW479.5FormulaC21H22FN3O5S2
CAS number
1632125-79-1
Molecular weight
479.5
Formula
C21H22FN3O5S2
Solubility
DMF: 5 mg/ml,DMF:PBS(pH 7·2)(1:1): 0·5 mg/ml,DMSO: 1 mg/ml
InChIKey
FVKOFZKSMMIUTL-UHFFFAOYSA-N
Catalogue number
GC44225
Brand
GLPBIO
Computed properties PubChem CID 57390068 · XLogP 1.6 · TPSA 113 Ų · H-bond donors 0
XLogP
1.6
TPSA
113 Ų
H-bond donors
0
H-bond acceptors
9
Rotatable bonds
4
Heavy atoms
32

SMILES C1COCCN1C2=C(C=C(C=C2)S(=O)(=O)N3CCOCC3)N4C(=O)C5=C(S4)C=CC(=C5)F

Computed descriptors from PubChem (CID 57390068), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.