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Chemical structure of GS-143

GC43786

GS-143

Also known as 4-[(4E)-3-benzyl-4-[[5-(2-fluorophenyl)furan-2-yl]methylidene]-5-oxopyrazol-1-yl]benzoic acid

GS-143 is an inhibitor of IκBα ubiquitylation

ChemicalCAS916232-21-8MW466.5FormulaC28H19FN2O4
CAS number
916232-21-8
Molecular weight
466.5
Formula
C28H19FN2O4
Solubility
10mg/mL in DMSO, 25mg/mL in DMF
InChIKey
IZPMWFSVTDOCDI-HAVVHWLPSA-N
Catalogue number
GC43786
Brand
GLPBIO
Computed properties PubChem CID 121513876 · XLogP 5.4 · TPSA 83.1 Ų · H-bond donors 1
XLogP
5.4
TPSA
83.1 Ų
H-bond donors
1
H-bond acceptors
6
Rotatable bonds
6
Heavy atoms
35

SMILES C1=CC=C(C=C1)CC\2=NN(C(=O)/C2=C/C3=CC=C(O3)C4=CC=CC=C4F)C5=CC=C(C=C5)C(=O)O

Computed descriptors from PubChem (CID 121513876), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
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Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
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Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.