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Chemical structure of GM 1489

GC43780

GM 1489

Also known as (3R)-3-[[(2S)-3-(1H-indol-3-yl)-1-oxo-1-[[(1S)-1-phenylethyl]amino]propan-2-yl]carbamoyl]-5-methylhexanoic acid

GM 1489 is a broad-spectrum inhibitor of matrix metalloproteinases (MMPs) with Ki values of 0·002, 0·1, 0·5, 0·2, and 20 μM for MMP-1, MMP-8, MMP-2, MMP-9, and MMP-3, respectively

ChemicalCAS171347-75-4MW463.6FormulaC27H33N3O4
CAS number
171347-75-4
Molecular weight
463.6
Formula
C27H33N3O4
Solubility
DMF: 50 mg/ml,DMSO: 50 mg/ml,Ethanol: 20 mg/ml,PBS (pH 7·2): 0·2 mg/ml
InChIKey
BLPWNGOQQLJQOL-NRYAXDJKSA-N
Catalogue number
GC43780
Brand
GLPBIO
Computed properties PubChem CID 10322165 · XLogP 3.3 · TPSA 111 Ų · H-bond donors 4
XLogP
3.3
TPSA
111 Ų
H-bond donors
4
H-bond acceptors
4
Rotatable bonds
11
Heavy atoms
34

SMILES C[C@@H](C1=CC=CC=C1)NC(=O)[C@H](CC2=CNC3=CC=CC=C32)NC(=O)[C@H](CC(C)C)CC(=O)O

Computed descriptors from PubChem (CID 10322165), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.