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Chemical structure of Davercin

GC43381

Davercin

Also known as (1R,2R,5R,6S,7S,8R,9R,11R,13R,14R)-8-[(2S,3R,4S,6R)-4-(dimethylamino)-3-hydroxy-6-methyloxan-2-yl]oxy-2-ethyl-9-hydroxy-6-[(2R,4R,5S,6S)-5-hydroxy-4-methoxy-4,6-dimethyloxan-2-yl]oxy-1,5,7,9,11,13-hexamethyl-3,15,17-trioxabicyclo[12.3.0]heptadecane-4,12,16-trione

Davercin is a macrolide antibiotic that inhibits bacterial protein synthesis by targeting the 50S ribosomal subunit, blocking the progression of nascent polypeptide chains

ChemicalCAS55224-05-0MW759.9FormulaC38H65NO14
CAS number
55224-05-0
Molecular weight
759.9
Formula
C38H65NO14
Solubility
DMF: 15 mg/ml,DMSO: 15 mg/ml,Ethanol: 30 mg/ml,Ethanol:PBS(pH 7·2) (1:1): 0·5 mg/ml
InChIKey
NKLGIWNNVDPGCA-ZDYKNUMJSA-N
Catalogue number
GC43381
Brand
GLPBIO
Computed properties PubChem CID 10033072 · XLogP 4.1 · TPSA 189 Ų · H-bond donors 3
XLogP
4.1
TPSA
189 Ų
H-bond donors
3
H-bond acceptors
15
Rotatable bonds
7
Heavy atoms
53

SMILES CC[C@@H]1[C@@]2([C@@H]([C@H](C(=O)[C@@H](C[C@@]([C@@H]([C@H]([C@@H]([C@H](C(=O)O1)C)O[C@H]3C[C@@]([C@H]([C@@H](O3)C)O)(C)OC)C)O[C@H]4[C@@H]([C@H](C[C@H](O4)C)N(C)C)O)(C)O)C)C)OC(=O)O2)C

Computed descriptors from PubChem (CID 10033072), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

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