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Chemical structure of Concanamycin B

GC43307

Concanamycin B

Also known as [6-[(4R)-2-[(4S)-4-[(4E,6E,11S,12R,13R,14E,16Z)-10,12-dihydroxy-3,17-dimethoxy-7,9,11,13,15-pentamethyl-18-oxo-1-oxacyclooctadeca-4,6,14,16-tetraen-2-yl]-3-hydroxypentan-2-yl]-2-hydroxy-5-methyl-6-[(E)-prop-1-enyl]oxan-4-yl]oxy-4-hydroxy-2-methyloxan-3-yl] carbamate

Concanamycin B is a macrolide antibiotic that selectively inhibits vacuolar type H+-ATPases, also known as V-ATPases (IC50 = 5 nM)

ChemicalCAS81552-33-2MW852.1FormulaC45H73NO14
CAS number
81552-33-2
Molecular weight
852.1
Formula
C45H73NO14
Solubility
DMF： soluble,DMSO： soluble,Ethanol： soluble,Methanol： soluble
InChIKey
AQXXGIBOZQZSAT-PJGWWKFTSA-N
Catalogue number
GC43307
Brand
GLPBIO
Computed properties PubChem CID 5468506 · XLogP 5.6 · TPSA 226 Ų · H-bond donors 6
XLogP
5.6
TPSA
226 Ų
H-bond donors
6
H-bond acceptors
14
Rotatable bonds
11
Heavy atoms
60

SMILES C/C=C/C1C([C@@H](CC(O1)(C(C)C([C@H](C)C2C(/C=C/C=C(/CC(C([C@@H]([C@@H]([C@@H](/C=C(/C=C(/C(=O)O2)\OC)\C)C)O)C)O)C)\C)OC)O)O)OC3CC(C(C(O3)C)OC(=O)N)O)C

Computed descriptors from PubChem (CID 5468506), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
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Pricing
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Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
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Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.