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Chemical structure of Cl2-SN-38

GC43277

Cl2-SN-38

Also known as [4-[[(2S)-6-amino-2-[[(2S)-2-[[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-[4-[[[4-[(2,5-dioxopyrrol-1-yl)methyl]cyclohexanecarbonyl]amino]methyl]triazol-1-yl]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethylamino]-2-oxoethoxy]acetyl]amino]-3-phenylpropanoyl]amino]hexanoyl]amino]phenyl]methyl [(19S)-10,19-diethyl-7-hydroxy-14,18-dioxo-17-oxa-3,13-diazapentacyclo[11.8.0.02,11.04,9.015,20]henicosa-1(21),2,4(9),5,7,10,15(20)-heptaen-19-yl] carbonate

CL2-SN-38 is a cleavable linker-based Drug-Linker conjugate, it can conjugate with the anti-Trop-2-humanized antibody hRS7· CL2-SN-38 can be used for the reasearch of cancer

ChemicalCAS1036969-20-6MW1627.8FormulaC82H106N12O23
CAS number
1036969-20-6
Molecular weight
1627.8
Formula
C82H106N12O23
Solubility
Soluble in DMSO
InChIKey
SSDFVXUQLUAHIC-DPMVZHECSA-N
Catalogue number
GC43277
Brand
GLPBIO
Computed properties PubChem CID 25139037 · XLogP 1.2 · TPSA 438 Ų · H-bond donors 7
XLogP
1.2
TPSA
438 Ų
H-bond donors
7
H-bond acceptors
27
Rotatable bonds
54
Heavy atoms
117

SMILES CCC1=C2CN3C(=CC4=C(C3=O)COC(=O)[C@@]4(CC)OC(=O)OCC5=CC=C(C=C5)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CC6=CC=CC=C6)NC(=O)COCC(=O)NCCOCCOCCOCCOCCOCCOCCOCCOCCN7C=C(N=N7)CNC(=O)C8CCC(CC8)CN9C(=O)C=CC9=O)C2=NC2=C1C=C(C=C2)O

Computed descriptors from PubChem (CID 25139037), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
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Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.