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Chemical structure of CAY10682

GC43190

CAY10682

Also known as 4-(4-bromophenyl)-1-[(4-fluorophenyl)methyl]-5-(3-imidazol-1-ylpropyl)-3-phenyl-4H-pyrrolo[3,4-d]pyrazol-6-one

(±)-Nutlin-3 blocks the interaction of p53 with its negative regulator Mdm2 (IC50 = 90 nM), inducing the expression of p53-regulated genes and blocking the growth of tumor xenografts in vivo

ChemicalCAS1542066-74-9MW570.5FormulaC30H25BrFN5O
CAS number
1542066-74-9
Molecular weight
570.5
Formula
C30H25BrFN5O
Solubility
DMF： 20 mg/ml,DMSO： 20 mg/ml,DMSO：PBS(pH 7·2) (1：2)： 0·25 mg/ml,Ethanol： 2 mg/ml
InChIKey
WBTRUQGSTZSFSK-UHFFFAOYSA-N
Catalogue number
GC43190
Brand
GLPBIO
Computed properties PubChem CID 90401380 · XLogP 5.4 · TPSA 56 Ų · H-bond donors 0
XLogP
5.4
TPSA
56 Ų
H-bond donors
0
H-bond acceptors
4
Rotatable bonds
8
Heavy atoms
38

SMILES C1=CC=C(C=C1)C2=NN(C3=C2C(N(C3=O)CCCN4C=CN=C4)C5=CC=C(C=C5)Br)CC6=CC=C(C=C6)F

Computed descriptors from PubChem (CID 90401380), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.