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Chemical structure of Avitinib

GC42884

Avitinib

Also known as N-[3-[[2-[3-fluoro-4-(4-methylpiperazin-1-yl)anilino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl]oxy]phenyl]prop-2-enamide

Avitinib is a pyrrolopyrimidine-based, irreversible inhibitor of the epidermal growth factor receptor (EGFR)

ChemicalCAS1557267-42-1MW487.5FormulaC26H26FN7O2
CAS number
1557267-42-1
Molecular weight
487.5
Formula
C26H26FN7O2
Solubility
DMF： 30 mg/ml,DMSO： 30 mg/ml,Ethanol： 30 mg/ml,Ethanol：PBS (pH 7·2) (1：10)： 0·9 mg/ml
InChIKey
UOFYSRZSLXWIQB-UHFFFAOYSA-N
Catalogue number
GC42884
Brand
GLPBIO
Computed properties PubChem CID 72734520 · XLogP 4.2 · TPSA 98.4 Ų · H-bond donors 3
XLogP
4.2
TPSA
98.4 Ų
H-bond donors
3
H-bond acceptors
8
Rotatable bonds
7
Heavy atoms
36

SMILES CN1CCN(CC1)C2=C(C=C(C=C2)NC3=NC4=C(C=CN4)C(=N3)OC5=CC=CC(=C5)NC(=O)C=C)F

Computed descriptors from PubChem (CID 72734520), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.