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Chemical structure of ARN14988

GC42854

ARN14988

Also known as 2-methylpropyl 5-chloro-3-(hexylcarbamoyl)-2,6-dioxopyrimidine-1-carboxylate

ARN14988 is a potent inhibitor of acid ceramidase (IC50 = 12·8 nM for the human enzyme)

ChemicalCAS1502027-70-4MW373.8FormulaC16H24ClN3O5
CAS number
1502027-70-4
Molecular weight
373.8
Formula
C16H24ClN3O5
Solubility
DMF: 30 mg/ml,DMSO: 30 mg/ml,DMSO:PBS (pH 7·2) (1:2): 0·33 mg/ml,Ethanol: slightly soluble
InChIKey
PBVLSEVDIRSYGE-UHFFFAOYSA-N
Catalogue number
GC42854
Brand
GLPBIO
Computed properties PubChem CID 72548973 · XLogP 4.2 · TPSA 96 Ų · H-bond donors 1
XLogP
4.2
TPSA
96 Ų
H-bond donors
1
H-bond acceptors
5
Rotatable bonds
8
Heavy atoms
25

SMILES CCCCCCNC(=O)N1C=C(C(=O)N(C1=O)C(=O)OCC(C)C)Cl

Computed descriptors from PubChem (CID 72548973), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.