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Chemical structure of Amifostine (hydrate)

GC42785

Amifostine (hydrate)

Also known as 2-(3-aminopropylamino)ethylsulfanylphosphonic acid;trihydrate

Amifostine (hydrate) (WR2721 trihydrate) is a broad-spectrum cytoprotective agent and a radioprotector· Amifostine (hydrate) selectively protects normal tissues from damage caused by radiation and chemotherapy· Amifostine (hydrate) is potent hypoxia-inducible factor-α1 (HIF-α1) and p53 inducer· Amifostine (hydrate) protects cells from damage by scavenging oxygen-derived free radicals· Amifostine (hydrate) reduces renal toxicity and has antiangiogenic action

ChemicalCAS112901-68-5MW268.3FormulaC5H15N2O3PS•3H2O
CAS number
112901-68-5
Molecular weight
268.3
Formula
C5H15N2O3PS•3H2O
Solubility
PBS (pH 7·2): 5 mg/ml
InChIKey
TXQPXJKRNHJWAX-UHFFFAOYSA-N
Catalogue number
GC42785
Brand
GLPBIO
Computed properties PubChem CID 148139 · TPSA 124 Ų · H-bond donors 7 · H-bond acceptors 9
TPSA
124 Ų
H-bond donors
7
H-bond acceptors
9
Rotatable bonds
7
Heavy atoms
15

SMILES C(CN)CNCCSP(=O)(O)O.O.O.O

Computed descriptors from PubChem (CID 148139), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

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