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Chemical structure of Akt Inhibitor IV

GC42759

Akt Inhibitor IV

Also known as N-[(E)-2-[5-(1,3-benzothiazol-2-yl)-3-ethyl-1-phenylbenzimidazol-3-ium-2-yl]ethenyl]-N-methylaniline iodide

Akt inhibitor IV is an inhibitor of Akt activation that inhibits Akt-mediated nuclear export of Forkhead box class O transcription factor 1a (FOXO1a; IC50 = 625 nM) and reduces phosphorylation of Akt at Ser473 and Thr308 in a dose-dependent manner

ChemicalCAS681281-88-9MW614.6FormulaC31H27N4S•I
CAS number
681281-88-9
Molecular weight
614.6
Formula
C31H27N4S•I
Solubility
DMF： 30 mg/ml,DMSO： 30 mg/ml,Ethanol： 30 mg/ml
InChIKey
NAYRELMNTQSBIN-UHFFFAOYSA-M
Catalogue number
GC42759
Brand
GLPBIO
Computed properties PubChem CID 5719375 · TPSA 53.2 Ų · H-bond donors 0 · H-bond acceptors 4
TPSA
53.2 Ų
H-bond donors
0
H-bond acceptors
4
Rotatable bonds
6
Heavy atoms
37

SMILES CC[N+]1=C(N(C2=C1C=C(C=C2)C3=NC4=CC=CC=C4S3)C5=CC=CC=C5)/C=C/N(C)C6=CC=CC=C6.[I-]

Computed descriptors from PubChem (CID 5719375), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
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Pricing
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Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.