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Chemical structure of Afuresertib Hydrochloride

GC42747

Afuresertib Hydrochloride

Also listed as Afuresertib (hydrochloride)

Afuresertib is a selective, orally bioavailable inhibitor of Akt1, 2, and 3 with Ki values of 0·08, 2, and 2·6 nM, respectively

ChemicalCAS1047645-82-8MW463.8FormulaC18H17Cl2FN4OS•HCl
CAS number
1047645-82-8
Molecular weight
463.8
Formula
C18H17Cl2FN4OS•HCl
Solubility
DMF： 50 mg/mL,DMSO： 30 mg/mL,Ethanol： 50 mg/mL,Ethanol：PBS(pH 7·2) (1：1)： 0·5 mg/mL
InChIKey
YFQJOPFTGMHYNV-YDALLXLXSA-N
Catalogue number
GC42747
Brand
GLPBIO
Computed properties PubChem CID 46843056 · TPSA 101 Ų · H-bond donors 3 · H-bond acceptors 5
TPSA
101 Ų
H-bond donors
3
H-bond acceptors
5
Rotatable bonds
6
Heavy atoms
28

SMILES CN1C(=C(C=N1)Cl)C2=C(SC(=C2)C(=O)N[C@@H](CC3=CC(=CC=C3)F)CN)Cl.Cl

Computed descriptors from PubChem (CID 46843056), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.