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Chemical structure of Ac-YVAD-CMK

GC42721

Ac-YVAD-CMK

Also known as (3S)-3-[[(2S)-2-[[(2S)-2-[[(2S)-2-acetamido-3-(4-hydroxyphenyl)propanoyl]amino]-3-methylbutanoyl]amino]propanoyl]amino]-5-chloro-4-oxopentanoic acid

Ac-YVAD-CMK is a selective irreversible inhibitor of caspase-1 (Ki=0·8nM), which can prevent the proinflammatory cytokine IL-1β activation· Ac-YVAD-CMK can reduce the inflammatory response and induce a long-lasting neuroprotective effect

ChemicalCAS178603-78-6MW541FormulaC24H33ClN4O8
CAS number
178603-78-6
Molecular weight
541
Formula
C24H33ClN4O8
Solubility
20mg/mL in DMSO, 10mg/mL in DMF
InChIKey
UOUBHJRCKHLGFB-DGJUNBOTSA-N
Catalogue number
GC42721
Brand
GLPBIO
Computed properties PubChem CID 9915279 · XLogP 0.9 · TPSA 191 Ų · H-bond donors 6
XLogP
0.9
TPSA
191 Ų
H-bond donors
6
H-bond acceptors
8
Rotatable bonds
14
Heavy atoms
37

SMILES C[C@@H](C(=O)N[C@@H](CC(=O)O)C(=O)CCl)NC(=O)[C@H](C(C)C)NC(=O)[C@H](CC1=CC=C(C=C1)O)NC(=O)C

Computed descriptors from PubChem (CID 9915279), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
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Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
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Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.