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Chemical structure of 5-Ethynyl-2'-deoxyuridine

GC42504

5-Ethynyl-2'-deoxyuridine

Also known as 5-ethynyl-1-[(2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrimidine-2,4-dione

5-ethynyl-2′-deoxyuridine (EdU), as a thymidine analoghas, a terminal alkyne group replacing a methyl group at the 5 position of the pyrimidine ring and can be readily incorporated into DNA during synthesis[1]

ChemicalCAS61135-33-9MW252.2FormulaC11H12N2O5
CAS number
61135-33-9
Molecular weight
252.2
Formula
C11H12N2O5
Solubility
DMF: 20 mg/mL,DMSO: 20 mg/mL; Water: 8 mg/mL (31·72 mM; ultrasonic and warming and heat to 37°C)
InChIKey
CDEURGJCGCHYFH-DJLDLDEBSA-N
Catalogue number
GC42504
Brand
GLPBIO
Computed properties PubChem CID 472172 · XLogP -1.3 · TPSA 99.1 Ų · H-bond donors 3
XLogP
-1.3
TPSA
99.1 Ų
H-bond donors
3
H-bond acceptors
5
Rotatable bonds
3
Heavy atoms
18

SMILES C#CC1=CN(C(=O)NC1=O)[C@H]2C[C@@H]([C@H](O2)CO)O

Computed descriptors from PubChem (CID 472172), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

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