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Chemical structure of 3-Aminopropylphosphonic Acid

GC42248

3-Aminopropylphosphonic Acid

Also known as 3-aminopropylphosphonic acid

3-Aminopropylphosphonic acid (3-APPA) is a phosphonic analog of GABA that acts as a partial agonist of GABAB receptors (IC50 = 1·5 μM in a radioligand binding assay)

ChemicalCAS13138-33-5MW139.1FormulaC3H10NO3P
CAS number
13138-33-5
Molecular weight
139.1
Formula
C3H10NO3P
Solubility
DMF: 5 mg/ml,DMSO: 2 mg/ml,Ethanol: 30 mg/ml,Ethanol:PBS (pH 7·2) (1:3): 0·25 mg/ml
InChIKey
GSZQTIFGANBTNF-UHFFFAOYSA-N
Catalogue number
GC42248
Brand
GLPBIO
Computed properties PubChem CID 97587 · XLogP -4.5 · TPSA 83.6 Ų · H-bond donors 3
XLogP
-4.5
TPSA
83.6 Ų
H-bond donors
3
H-bond acceptors
4
Rotatable bonds
3
Heavy atoms
8

SMILES C(CN)CP(=O)(O)O

Computed descriptors from PubChem (CID 97587), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

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