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Chemical structure of 6-diazo-5-oxo-L-nor-Leucine

GC41224

6-diazo-5-oxo-L-nor-Leucine

Also known as 2-amino-6-diazo-5-oxohexanoic acid

6-Diazo-5-oxo-L-nor-Leucine (DON) is a glutamine analog that inhibits glutaminases, a selective, mechanism-based inactivator of glutamine-using enzymes

ChemicalCAS157-03-9MW171.2FormulaC6H9N3O3
CAS number
157-03-9
Molecular weight
171.2
Formula
C6H9N3O3
Solubility
>1mg/mL in DMSO, >10mg/mL in Water(Need warm the tube at 50 ℃ and shake it in the ultrasonic bath for a while)
InChIKey
YCWQAMGASJSUIP-UHFFFAOYSA-N
Catalogue number
GC41224
Brand
GLPBIO
Computed properties PubChem CID 164 · XLogP -3.5 · TPSA 82.4 Ų · H-bond donors 2
XLogP
-3.5
TPSA
82.4 Ų
H-bond donors
2
H-bond acceptors
5
Rotatable bonds
5
Heavy atoms
12

SMILES C(CC(=O)C=[N+]=[N-])C(C(=O)O)N

Computed descriptors from PubChem (CID 164), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

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