
GC39840
AMI-1 free acid
Also known as 4-hydroxy-7-[(5-hydroxy-7-sulfonaphthalen-2-yl)carbamoylamino]naphthalene-2-sulfonic acid
AMI-1 free acid is a potent, cell-permeable and reversible inhibitor of protein arginine N-methyltransferases (PRMTs), with IC50s of 8·8 μM and 3·0 μM for human PRMT1 and yeast-Hmt1p, respectively· AMI-1 free acid exerts PRMTs inhibitory effects by blocking peptide-substrate binding
ChemicalCAS134-47-4MW504.49FormulaC21H16N2O9S2
- CAS number
- 134-47-4
- Molecular weight
- 504.49
- Formula
- C21H16N2O9S2
- Solubility
- DMSO: 83·33 mg/mL (165·18 mM)
- InChIKey
- PCGISRHGYLRXSR-UHFFFAOYSA-N
- Catalogue number
- GC39840
- Brand
- GLPBIO
Computed properties PubChem CID 67254 · XLogP 1.8 · TPSA 207 Ų · H-bond donors 6
- XLogP
- 1.8
- TPSA
- 207 Ų
- H-bond donors
- 6
- H-bond acceptors
- 9
- Rotatable bonds
- 4
- Heavy atoms
- 34
SMILES C1=CC2=C(C=C(C=C2C=C1NC(=O)NC3=CC4=CC(=CC(=C4C=C3)O)S(=O)(=O)O)S(=O)(=O)O)O
Computed descriptors from PubChem (CID 67254), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.
Ordering in Israel
- Lead time
- Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
- Pricing
- Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
- Documents
- Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
- Who we serve
- Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.
- Questions
- WhatsApp · +972-55-990-7576 · orders@labo.co.il