GC39754
SR18662
Also known as (E)-3-(3,4-dichlorophenyl)-N-[2-(4-methylsulfonylpiperazin-1-yl)-2-oxoethyl]prop-2-enamide
SR18662 is a potent inhibitor of Krüppel-like factor five (KLF5) with an IC50?of 4·4 nM and an analogue of ML264 with improved inhibitory potency against colorectal cancer cells· SR18662 can be used for the study of colorectal cancer
ChemicalCAS2505001-62-5MW420.31FormulaC16H19Cl2N3O4S
- CAS number
- 2505001-62-5
- Molecular weight
- 420.31
- Formula
- C16H19Cl2N3O4S
- Solubility
- DMSO： 125 mg/mL (297·40 mM)
- InChIKey
- WUJBXFXHDUVSFM-HWKANZROSA-N
- Catalogue number
- GC39754
- Brand
- GLPBIO
Computed properties PubChem CID 146674222 · XLogP 1.5 · TPSA 95.2 Ų · H-bond donors 1
- XLogP
- 1.5
- TPSA
- 95.2 Ų
- H-bond donors
- 1
- H-bond acceptors
- 5
- Rotatable bonds
- 5
- Heavy atoms
- 26
SMILES CS(=O)(=O)N1CCN(CC1)C(=O)CNC(=O)/C=C/C2=CC(=C(C=C2)Cl)Cl
Computed descriptors from PubChem (CID 146674222), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.
Ordering in Israel
- Lead time
- Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
- Pricing
- Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
- Documents
- Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
- Who we serve
- Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.
- Questions
- WhatsApp · +972-55-990-7576 · orders@labo.co.il