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Chemical structure of Nigericin

GC39719

Nigericin

Also known as (2R)-2-[(2R,3S,6R)-6-[[(2S,4R,5R,6R,7R,9R)-2-[(2R,5S)-5-[(2R,3S,5R)-5-[(2S,3S,5R,6R)-6-hydroxy-6-(hydroxymethyl)-3,5-dimethyloxan-2-yl]-3-methyloxolan-2-yl]-5-methyloxolan-2-yl]-7-methoxy-2,4,6-trimethyl-1,10-dioxaspiro[4.5]decan-9-yl]methyl]-3-methyloxan-2-yl]propanoic acid

K+/H+ ionophore,promoting K+/H+ exchange across mitochondrial membrane

ChemicalCAS28380-24-7MW724.96FormulaC40H68O11
CAS number
28380-24-7
Molecular weight
724.96
Formula
C40H68O11
Solubility
1·2mg/mL in DMF, 20mg/mL in Ethanol
InChIKey
DANUORFCFTYTSZ-SJSJOXFOSA-N
Catalogue number
GC39719
Brand
GLPBIO
Computed properties PubChem CID 34230 · XLogP 5.5 · TPSA 142 Ų · H-bond donors 3
XLogP
5.5
TPSA
142 Ų
H-bond donors
3
H-bond acceptors
11
Rotatable bonds
9
Heavy atoms
51

SMILES C[C@H]1CC[C@@H](O[C@H]1[C@@H](C)C(=O)O)C[C@@H]2C[C@H]([C@H]([C@@]3(O2)[C@@H](C[C@@](O3)(C)[C@H]4CC[C@@](O4)(C)[C@H]5[C@H](C[C@@H](O5)[C@@H]6[C@H](C[C@H]([C@@](O6)(CO)O)C)C)C)C)C)OC

Computed descriptors from PubChem (CID 34230), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.