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Chemical structure of CMP-5

GC39665

CMP-5

Also known as 1-(9-ethylcarbazol-3-yl)-N-(pyridin-2-ylmethyl)methanamine

CMP-5 is a potent, specific, and selective PRMT5 inhibitor, while displays no activity against PRMT1, PRMT4, and PRMT7 enzymes· CMP-5 selectively blocks S2Me-H4R3 by inhibiting PRMT5 methyltransferase activity on histone preparations· CMP-5 prevents Epstein-Barr virus (EBV)-driven B-lymphocyte transformation but leaving normal B cells unaffected

ChemicalCAS880813-42-3MW315.41FormulaC21H21N3
CAS number
880813-42-3
Molecular weight
315.41
Formula
C21H21N3
Solubility
DMSO： 125 mg/mL (396·31 mM)
InChIKey
YPJMOVVQKBFRNH-UHFFFAOYSA-N
Catalogue number
GC39665
Brand
GLPBIO
Computed properties PubChem CID 4722595 · XLogP 3.5 · TPSA 29.9 Ų · H-bond donors 1
XLogP
3.5
TPSA
29.9 Ų
H-bond donors
1
H-bond acceptors
2
Rotatable bonds
5
Heavy atoms
24

SMILES CCN1C2=C(C=C(C=C2)CNCC3=CC=CC=N3)C4=CC=CC=C41

Computed descriptors from PubChem (CID 4722595), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.