GC39650
Navitoclax-piperazine
Also known as 4-[4-[[2-(4-chlorophenyl)-5,5-dimethylcyclohexen-1-yl]methyl]piperazin-1-yl]-N-[4-[[(2R)-1-phenylsulfanyl-4-piperazin-1-ylbutan-2-yl]amino]-3-(trifluoromethylsulfonyl)phenyl]sulfonylbenzamide
Navitoclax-piperazine (ABT-263-piperazine) is a B-cell lymphoma extra large (BCL-XL) inhibitor· Navitoclax-piperazine and a VHL ligand for the E3 ubiquitin ligase can be used in the synthesis of PROTAC DT2216
ChemicalCAS2143096-93-7MW973.63FormulaC47H56ClF3N6O5S3
- CAS number
- 2143096-93-7
- Molecular weight
- 973.63
- Formula
- C47H56ClF3N6O5S3
- Solubility
- DMSO： 250 mg/mL (256·77 mM)
- InChIKey
- CRPNZDFOWRFBLZ-KXQOOQHDSA-N
- Catalogue number
- GC39650
- Brand
- GLPBIO
Computed properties PubChem CID 132020434 · XLogP 9.3 · TPSA 173 Ų · H-bond donors 3
- XLogP
- 9.3
- TPSA
- 173 Ų
- H-bond donors
- 3
- H-bond acceptors
- 14
- Rotatable bonds
- 16
- Heavy atoms
- 65
SMILES CC1(CCC(=C(C1)CN2CCN(CC2)C3=CC=C(C=C3)C(=O)NS(=O)(=O)C4=CC(=C(C=C4)N[C@H](CCN5CCNCC5)CSC6=CC=CC=C6)S(=O)(=O)C(F)(F)F)C7=CC=C(C=C7)Cl)C
Computed descriptors from PubChem (CID 132020434), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.
Ordering in Israel
- Lead time
- Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
- Pricing
- Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
- Documents
- Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
- Who we serve
- Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.
- Questions
- WhatsApp · +972-55-990-7576 · orders@labo.co.il