Loading...
Chemical structure of Gartisertib

GC39645

Gartisertib

Also listed as ATR inhibitor 2

ATR inhibitor 2 (VX-803) is an ATP-competitive, orally active, and selective ATR inhibitor, with a Ki of ＜150 pM· ATR inhibitor 2 potently inhibits ATR-driven phosphorylated checkpoint kinase-1 (Chk1) phosphorylation with an IC50 of 8 nM· Antitumor activity

ChemicalCAS1613191-99-3MW541.55FormulaC25H29F2N9O3
CAS number
1613191-99-3
Molecular weight
541.55
Formula
C25H29F2N9O3
Solubility
DMSO： 25 mg/mL (46·16 mM)
InChIKey
QAYHKBLKSXWOEO-UHFFFAOYSA-N
Catalogue number
GC39645
Brand
GLPBIO
Computed properties PubChem CID 86720912 · XLogP 0.1 · TPSA 134 Ų · H-bond donors 2
XLogP
0.1
TPSA
134 Ų
H-bond donors
2
H-bond acceptors
11
Rotatable bonds
5
Heavy atoms
39

SMILES C1CN(CCC1C(=O)N2CCN(CC2)C3COC3)C4=C(C=NC=C4NC(=O)C5=C6N=CC(=CN6N=C5N)F)F

Computed descriptors from PubChem (CID 86720912), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.