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Chemical structure of Giredestrant

GC39630

Giredestrant

Also known as 3-[(1R,3R)-1-[2,6-difluoro-4-[[1-(3-fluoropropyl)azetidin-3-yl]amino]phenyl]-3-methyl-1,3,4,9-tetrahydropyrido[3,4-b]indol-2-yl]-2,2-difluoropropan-1-ol

Giredestrant is an oral selective estrogen receptor (ER) degrader· Giredestrant can induce an inactive conformation of the estrogen receptor ligand binding domain and promoting proteasome-mediated degradation of the receptor protein· Giredestrant is used to treat estrogen receptor-positive (ER+) breast cancer

ChemicalCAS1953133-47-5MW522.55FormulaC27H31F5N4O
CAS number
1953133-47-5
Molecular weight
522.55
Formula
C27H31F5N4O
Solubility
Soluble in DMSO
InChIKey
GQCXHIKRWBIQMD-AKJBCIBTSA-N
Catalogue number
GC39630
Brand
GLPBIO
Computed properties PubChem CID 121410806 · XLogP 4.8 · TPSA 54.5 Ų · H-bond donors 3
XLogP
4.8
TPSA
54.5 Ų
H-bond donors
3
H-bond acceptors
9
Rotatable bonds
9
Heavy atoms
37

SMILES C[C@@H]1CC2=C([C@H](N1CC(CO)(F)F)C3=C(C=C(C=C3F)NC4CN(C4)CCCF)F)NC5=CC=CC=C25

Computed descriptors from PubChem (CID 121410806), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.