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Chemical structure of CWP232228

GC39626

CWP232228

Also known as disodium;[4-[[(6S,9aS)-1-(benzylcarbamoyl)-8-[(2-methylindazol-7-yl)methyl]-4,7-dioxo-2-prop-2-enyl-3,6,9,9a-tetrahydropyrazino[2,1-c][1,2,4]triazin-6-yl]methyl]phenyl] phosphate

CWP232228, a highly potent selective Wnt/β-catenin signaling inhibitor, antagonizes binding of β-catenin to T-cell factor (TCF) in the nucleus· CWP232228 suppresses tumor formation and metastasis without toxicity through the inhibition of the growth of breast and liver cancer stem cells (CSCs)

ChemicalCAS1144044-02-9MW717.62FormulaC33H34N7Na2O7P
CAS number
1144044-02-9
Molecular weight
717.62
Formula
C33H34N7Na2O7P
Solubility
Soluble in DMSO
InChIKey
KKMKZLQVDAGSOA-GDUXWEAWSA-L
Catalogue number
GC39626
Brand
GLPBIO
Computed properties PubChem CID 71509158 · TPSA 166 Ų · H-bond donors 1 · H-bond acceptors 9
TPSA
166 Ų
H-bond donors
1
H-bond acceptors
9
Rotatable bonds
9
Heavy atoms
50

SMILES CN1C=C2C=CC=C(C2=N1)CN3C[C@H]4N([C@H](C3=O)CC5=CC=C(C=C5)OP(=O)([O-])[O-])C(=O)CN(N4C(=O)NCC6=CC=CC=C6)CC=C.[Na+].[Na+]

Computed descriptors from PubChem (CID 71509158), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
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Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.