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Chemical structure of Dorzagliatin

GC39529

Dorzagliatin

Also known as (2S)-2-[3-(2-chlorophenoxy)-5-oxo-2H-pyrrol-1-yl]-N-[1-[(2R)-2,3-dihydroxypropyl]pyrazol-3-yl]-4-methylpentanamide

Dorzagliatin (HMS5552), a dual-acting glucokinase (GK) activator, improves glycaemic control and pancreatic β-cell function in type 2 diabetes

ChemicalCAS1191995-00-2MW462.93FormulaC22H27ClN4O5
CAS number
1191995-00-2
Molecular weight
462.93
Formula
C22H27ClN4O5
Solubility
DMSO： 125 mg/mL (270·02 mM)
InChIKey
HMUMWSORCUWQJO-QAPCUYQASA-N
Catalogue number
GC39529
Brand
GLPBIO
Computed properties PubChem CID 57920094 · XLogP 1.6 · TPSA 117 Ų · H-bond donors 3
XLogP
1.6
TPSA
117 Ų
H-bond donors
3
H-bond acceptors
6
Rotatable bonds
10
Heavy atoms
32

SMILES CC(C)C[C@@H](C(=O)NC1=NN(C=C1)C[C@H](CO)O)N2CC(=CC2=O)OC3=CC=CC=C3Cl

Computed descriptors from PubChem (CID 57920094), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
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Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.