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Chemical structure of sulfo-SPDB

GC39447

sulfo-SPDB

Also known as 1-(2,5-dioxopyrrolidin-1-yl)oxy-1-oxo-4-(pyridin-2-yldisulfanyl)butane-2-sulfonic acid

sulfo-SPDB is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)

ChemicalCAS1193111-39-5MW406.45FormulaC13H14N2O7S3
CAS number
1193111-39-5
Molecular weight
406.45
Formula
C13H14N2O7S3
Solubility
Soluble in DMSO
InChIKey
FUHCFUVCWLZEDQ-UHFFFAOYSA-N
Catalogue number
GC39447
Brand
GLPBIO
Computed properties PubChem CID 53248044 · XLogP 0 · TPSA 190 Ų · H-bond donors 1
XLogP
0
TPSA
190 Ų
H-bond donors
1
H-bond acceptors
10
Rotatable bonds
9
Heavy atoms
25

SMILES C1CC(=O)N(C1=O)OC(=O)C(CCSSC2=CC=CC=N2)S(=O)(=O)O

Computed descriptors from PubChem (CID 53248044), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

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