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Chemical structure of Lp-PLA2-IN-3

GC39397

Lp-PLA2-IN-3

Also known as 4-amino-N-[4-[4-chloro-3-(trifluoromethyl)phenoxy]-3-cyanophenyl]benzenesulfonamide

Lp-PLA2-IN-3 is a potent and orally bioavailable lipoprotein-associated phospholipase A2 (Lp-PLA2) inhibitor, with an IC50 of 14 nM for recombinant human Lp-PLA2 (rhLpPLA2)

ChemicalCAS2196245-16-4MW467.85FormulaC20H13ClF3N3O3S
CAS number
2196245-16-4
Molecular weight
467.85
Formula
C20H13ClF3N3O3S
Solubility
DMSO: ≥ 250 mg/mL (534·36 mM)
InChIKey
GADGQEKPNKSGMT-UHFFFAOYSA-N
Catalogue number
GC39397
Brand
GLPBIO
Computed properties PubChem CID 132427687 · XLogP 4.5 · TPSA 114 Ų · H-bond donors 2
XLogP
4.5
TPSA
114 Ų
H-bond donors
2
H-bond acceptors
9
Rotatable bonds
5
Heavy atoms
31

SMILES C1=CC(=CC=C1N)S(=O)(=O)NC2=CC(=C(C=C2)OC3=CC(=C(C=C3)Cl)C(F)(F)F)C#N

Computed descriptors from PubChem (CID 132427687), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
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Pricing
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Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
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Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.