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Chemical structure of Fz7-21 TFA

GC39383

Fz7-21 TFA

Fz7-21 (Ac-LPSDDLEFWCHVMY-NH2) TFA is a potent peptide antagonist of FZD7 receptors , selectively binds to FZD7 CRD subclass and alters the conformation of the CRD and the architecture of its lipid-binding groove· The EC50 values are 58 and 34 nM for human and mouse FZD7 CRD, respectively· Fz7-21 TFA impairs the function of FZD7 in Wnt-β-catenin signalling and stem cell function in intestinal organoids

ChemicalMW1910.07FormulaC85H115N18F3O25S2
CAS number
Molecular weight
1910.07
Formula
C85H115N18F3O25S2
Solubility
DMSO: 33·33 mg/mL (17·45 mM); Water: < 0·1 mg/mL (insoluble)
Catalogue number
GC39383
Brand
GLPBIO

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
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Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.