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Chemical structure of AZD7325

GC39342

AZD7325

Also known as 4-amino-8-(2-fluoro-6-methoxyphenyl)-N-propylcinnoline-3-carboxamide

AZD7325 is a potent and orally active partial selective PAM of GABAAα2 and Aα3 receptor (Ki=0·3 and 1·3 nM, respectively), and has less antagonistic efficacy at the Aα1?and Aα5?receptor subtypes

ChemicalCAS942437-37-8MW354.38FormulaC19H19FN4O2
CAS number
942437-37-8
Molecular weight
354.38
Formula
C19H19FN4O2
Solubility
DMSO： 250 mg/mL (705·46 mM)
InChIKey
KYDURMHFWXCKMW-UHFFFAOYSA-N
Catalogue number
GC39342
Brand
GLPBIO
Computed properties PubChem CID 23581869 · XLogP 3.3 · TPSA 90.1 Ų · H-bond donors 2
XLogP
3.3
TPSA
90.1 Ų
H-bond donors
2
H-bond acceptors
6
Rotatable bonds
5
Heavy atoms
26

SMILES CCCNC(=O)C1=NN=C2C(=C1N)C=CC=C2C3=C(C=CC=C3F)OC

Computed descriptors from PubChem (CID 23581869), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
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Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.