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Chemical structure of Rheb inhibitor NR1

GC39292

Rheb inhibitor NR1

Also known as 4-bromo-6-(3,4-dichlorophenyl)sulfanyl-1-[[4-(dimethylcarbamoyl)phenyl]methyl]indole-2-carboxylic acid

Rheb inhibitor NR1 is a Rheb inhibitor with an IC50 of 2·1??M in the Rheb-IVK assay

ChemicalCAS2216763-38-9MW578.3FormulaC25H19BrCl2N2O3S
CAS number
2216763-38-9
Molecular weight
578.3
Formula
C25H19BrCl2N2O3S
Solubility
DMSO: 100 mg/mL (172·92 mM)
InChIKey
MJYFVDNMTKLGTH-UHFFFAOYSA-N
Catalogue number
GC39292
Brand
GLPBIO
Computed properties PubChem CID 132281917 · XLogP 6.9 · TPSA 87.8 Ų · H-bond donors 1
XLogP
6.9
TPSA
87.8 Ų
H-bond donors
1
H-bond acceptors
4
Rotatable bonds
6
Heavy atoms
34

SMILES CN(C)C(=O)C1=CC=C(C=C1)CN2C(=CC3=C2C=C(C=C3Br)SC4=CC(=C(C=C4)Cl)Cl)C(=O)O

Computed descriptors from PubChem (CID 132281917), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
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Documents
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