GC39282
COH34
Also known as 1-[(4-methylphenyl)sulfanyliminomethyl]naphthalen-2-ol
COH34 is a potent and specific poly(ADP-ribose) glycohydrolase (PARG) inhibitor with an IC50 of 0·37 nM· COH34 binds to the catalytic domain of PARG (Kd=0·547 μM), thereby prolonging PARylation at DNA lesions and trapping DNA repair factors
ChemicalCAS906439-72-3MW293.38FormulaC18H15NOS
- CAS number
- 906439-72-3
- Molecular weight
- 293.38
- Formula
- C18H15NOS
- Solubility
- DMSO： 16·67 mg/mL (56·82 mM)
- InChIKey
- SFUAIBHPGDRCFL-UHFFFAOYSA-N
- Catalogue number
- GC39282
- Brand
- GLPBIO
Computed properties PubChem CID 303171 · XLogP 4.9 · TPSA 57.9 Ų · H-bond donors 1
- XLogP
- 4.9
- TPSA
- 57.9 Ų
- H-bond donors
- 1
- H-bond acceptors
- 3
- Rotatable bonds
- 3
- Heavy atoms
- 21
SMILES CC1=CC=C(C=C1)SN=CC2=C(C=CC3=CC=CC=C32)O
Computed descriptors from PubChem (CID 303171), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.
Ordering in Israel
- Lead time
- Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
- Pricing
- Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
- Documents
- Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
- Who we serve
- Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.
- Questions
- WhatsApp · +972-55-990-7576 · orders@labo.co.il