Loading...
Chemical structure of GS-443902

GC39240

GS-443902

Also known as [[(2R,3S,4R,5R)-5-(4-aminopyrrolo[2,1-f][1,2,4]triazin-7-yl)-5-cyano-3,4-dihydroxyoxolan-2-yl]methoxy-hydroxyphosphoryl] phosphono hydrogen phosphate

GS-443902 (GS-441524 triphosphate) is a potent viral RNA-dependent RNA-polymerases (RdRp) inhibitor with IC50s of 1·1 ?M, 5 ?M for RSV RdRp and HCV RdRp, respectively

ChemicalCAS1355149-45-9MW531.2FormulaC12H16N5O13P3
CAS number
1355149-45-9
Molecular weight
531.2
Formula
C12H16N5O13P3
Solubility
Water： 100 mg/mL (188·25 mM)
InChIKey
DFVPCNAMNAPBCX-LTGWCKQJSA-N
Catalogue number
GC39240
Brand
GLPBIO
Computed properties PubChem CID 56832906 · XLogP -5.3 · TPSA 290 Ų · H-bond donors 7
XLogP
-5.3
TPSA
290 Ų
H-bond donors
7
H-bond acceptors
17
Rotatable bonds
8
Heavy atoms
33

SMILES C1=C2C(=NC=NN2C(=C1)[C@]3([C@@H]([C@@H]([C@H](O3)COP(=O)(O)OP(=O)(O)OP(=O)(O)O)O)O)C#N)N

Computed descriptors from PubChem (CID 56832906), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.