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Chemical structure of PROTAC BRD4 ligand-1

GC39180

PROTAC BRD4 ligand-1

Also known as 8-(3,5-difluoro-2-pyridinyl)-15-methyl-4-(methylsulfonylmethyl)-14-oxo-8,12,15-triazatetracyclo[8.6.1.02,7.013,17]heptadeca-1(16),2(7),3,5,10,13(17)-hexaene-5-carboxylic acid

PROTAC BRD4 ligand-1 is a potent BET inhibitor and a ligand for target BRD4 protein for PROTACT GNE-987

ChemicalCAS2313230-51-0MW500.47FormulaC23H18F2N4O5S
CAS number
2313230-51-0
Molecular weight
500.47
Formula
C23H18F2N4O5S
Solubility
DMSO： 5 mg/mL (9·99 mM)
InChIKey
BSYGSSMAXOMCQE-UHFFFAOYSA-N
Catalogue number
GC39180
Brand
GLPBIO
Computed properties PubChem CID 142572767 · XLogP 1.2 · TPSA 132 Ų · H-bond donors 2
XLogP
1.2
TPSA
132 Ų
H-bond donors
2
H-bond acceptors
9
Rotatable bonds
4
Heavy atoms
35

SMILES CN1C=C2C3=C(C=C(C(=C3)CS(=O)(=O)C)C(=O)O)N(CC4=CNC(=C42)C1=O)C5=C(C=C(C=N5)F)F

Computed descriptors from PubChem (CID 142572767), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.