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Chemical structure of PI-273

GC39155

PI-273

Also known as 2-[(4-chlorobenzoyl)carbamothioylamino]-4-ethyl-5-methylthiophene-3-carboxamide

PI-273 is a first reversibly and specific phosphatidylinositol 4-kinase (PI4KIIα) inhibitor with an IC50 of 0·47 μM· PI-273 can inhibit breast cancer cell proliferation, block the cell cycle and induce cell apoptosis

ChemicalCAS925069-34-7MW381.9FormulaC16H16ClN3O2S2
CAS number
925069-34-7
Molecular weight
381.9
Formula
C16H16ClN3O2S2
Solubility
DMSO： 6·25 mg/mL (16·37 mM)
InChIKey
MIERMBQDBLFAFW-UHFFFAOYSA-N
Catalogue number
GC39155
Brand
GLPBIO
Computed properties PubChem CID 17168969 · XLogP 4.2 · TPSA 145 Ų · H-bond donors 3
XLogP
4.2
TPSA
145 Ų
H-bond donors
3
H-bond acceptors
4
Rotatable bonds
4
Heavy atoms
24

SMILES CCC1=C(SC(=C1C(=O)N)NC(=S)NC(=O)C2=CC=C(C=C2)Cl)C

Computed descriptors from PubChem (CID 17168969), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.