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Chemical structure of N-Desmethyltamoxifen hydrochloride

GC38931

N-Desmethyltamoxifen hydrochloride

Also known as 2-[4-[(Z)-1,2-diphenylbut-1-enyl]phenoxy]-N-methylethanamine;hydrochloride

N-Desmethyltamoxifen hydrochloride is the major metabolite of tamoxifen in humans· N-Desmethyltamoxifen, a poor antiestrogen, is a ten-fold more potent protein kinase C (PKC) inhibitor than Tamoxifen· N-Desmethyltamoxifen hydrochloride is also a potent regulator of ceramide metabolism in human AML cells, limiting ceramide glycosylation, hydrolysis, and sphingosine phosphorylation

ChemicalCAS15917-65-4MW393.95FormulaC25H28ClNO
CAS number
15917-65-4
Molecular weight
393.95
Formula
C25H28ClNO
Solubility
DMSO： 83·33 mg/mL (211·52 mM)
InChIKey
GMLHJWZEYLTNJW-BJFQDICYSA-N
Catalogue number
GC38931
Brand
GLPBIO
Computed properties PubChem CID 24200424 · TPSA 21.3 Ų · H-bond donors 2 · H-bond acceptors 2
TPSA
21.3 Ų
H-bond donors
2
H-bond acceptors
2
Rotatable bonds
8
Heavy atoms
28

SMILES CC/C(=C(\C1=CC=CC=C1)/C2=CC=C(C=C2)OCCNC)/C3=CC=CC=C3.Cl

Computed descriptors from PubChem (CID 24200424), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
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Pricing
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Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
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Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.